Nutr Rev. 2019 Jun 22. Epub 2019 Jun 22. PMID: 31228241
Impact of anthocyanin-rich whole fruit consumption on exercise-induced oxidative stress and inflammation: a systematic review and meta-analysis.
CONTEXT: Supplementing with fruits high in anthocyanins to reduce exercise-induced oxidative stress and inflammation has produced mixed results.OBJECTIVE: This systematic review and meta-analysis aims to discuss the impact of whole fruits high in anthocyanins, including processing methods and the type and amount of fruit, on inflammation and oxidative stress.DATA SOURCES: PICOS reporting guidelines and a customized coding scheme were used to search 5 databases (SPORTDiscus, Science Direct, Web of Science [BIOSIS], Medline [Pubmed], and the Cochrane Collaboration) with additional cross-referencing selection.DATA EXTRACTION: A random-effects meta-analysis was used to measure effects of the fruit supplements with 3 statistics; the QTotal value based on aχ2 distribution, τ2 value, and I2 value were used to determine homogeneity of variances on 22 studies (out of 807). Outliers were identified using a relative residual value.RESULTS: A small significant negative summary effect across the sum of all inflammatory marker outcomes (P0.05) differences between subgrouping variables.CONCLUSIONS: Results indicate that consumption of whole fruit high in anthocyanins can be beneficial for reducing inflammation and oxidative stress.