Nutrients. 2019 Dec 18 ;12(1). Epub 2019 Dec 18. PMID: 31861307
Selenium Supplementation and Prostate Health in a New Zealand Cohort.
BACKGROUND: There is variable reporting on the benefits of a 200μg/d selenium supplementation towards reducing prostate cancer impacts. The current analysis is to understand whether stratified groups receive supplementation benefits on prostate health.METHODS: 572 men were supplemented with 200µg/d selenium as selinized yeast for six months, and 481 completed the protocol. Selenium and prostate-specific antigen (PSA) levels were measured in serum at pre- and post-supplementation. Changes in selenium and PSA levels subsequent to supplementation were assessed with and without demographic,lifestyle, genetic and dietary stratifications.RESULTS: The post-supplementation selenium (= 0.002) and the gain in selenium (