Int Immunol. 2020 Mar 27. Epub 2020 Mar 27. PMID: 32219308
Diversity of energy metabolism in immune responses regulated by microorganisms and dietary nutrition.
Immune metabolism has been recognized as a new paradigm in the regulation of host immunity. In the environment, there are many microorganisms including pathogenic and non-pathogenic and/or beneficial ones. Immune cells exhibit various responses against different types of microbes, which seem to be associated with changes in energy metabolism. In addition, dietary nutrition influences host metabolism and consequent responses by immune cells. In this review, we describe the complex network of immune metabolism from the perspectives of nutrition, microorganisms and host immunity for the control of immunologic health and diseases.